2008 ~ 2013    서울시립대 (이학박사) 

2006 ~ 2008    서울시립대 (이학석사) 

1997 ~ 2006    서울시립대 (이학사) 

2025 ~ 현재   대구가톨릭대학교 의과대학 조교수

2022 ~ 2025  대구경북첨단의료산업진흥재단 신약개발지원센터 선임연구원/팀장

2025           경북대학교 생명공학부 겸임교수

2019 ~ 2022  대구경북첨단의료산업진흥재단 신약개발지원센터 선임연구원

2017 ~ 2019  Oklahoma Medical Research Foundation, Research Assistant Member

2013 ~ 2017  Oklahoma Medical Research Foundation, Postdoctoral Fellow

2013           서울시립대학교 연구교수      

2026 한국세포생물학회 홍보위원장

       한국통합생물학회 뉴스지편집위원장

       한국분자·세포생물학회 대구경북분회 총무

       한국유전학회 ICGSK 추진위원회 위원

 

2025 한국통합생물학회 산학연협력위원장

       한국분자·세포생물학회 기획위원회 위원

       한국유전학회 ICGSK 추진위원회 위원

 

2024 한국분자·세포생물학회 기획위원회 위원

       한국통합생물학회 조직위원회 위원

       한국유전학회 산학위원회 위원

       생화학분자생물학회 산학위원회, 운영위원회 위원

 

2023 생화학분자생물학회 차기위원회 위원

29. Chang SH, Jang J, Yang W, Lee NK, Choi S, Jung HI, Kim W, Cha B, Yoon SJ, Noh JY, Lee J. Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation. Front Toxicol. 2025 Sep 9;7:1636246. (JCR IF:4.6)

 

28. Lim JY, Choi EH, Kim Y, Kim M, Choi D, Kim W#, Cha B#. Identification of YAP regulators through high-throughput screening and NanoBiT-based validation-drug repositioning for cancer therapy. Anim Cells Syst. 2025 2025, May 8;29(1):325-338. (#co-corresponding author) (JCR IF: 3.2)  

 

27. Jeon SY, Jeon Y, Lim JY, Kim Y, Cha B#, Kim W#. Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets. Signal Transduct Target Ther. 2025 Jan 6;10(1):4. (#co-corresponding author) (JCR IF: 52.7)

 

26. Jeon Y, Jeon S, Lim JY, Koh H, Choi CW, Seong SK, Cha B#, Kim W#. Monocyte Activation Test (MAT) as an Ethical Alternative to Animal Testing. BMB Rep. 2025 Mar;58(3):105-115. (#co-corresponding author) (JCR IF: 3.3)

 

25. Choi YS, Kim YJ, Jeon Y, Kang JS, Lee J, Hong E, Park YH, Kim W#, Cha B#, Jeon R# . Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives. J Enzyme Inhib Med Chem. 2024 39(1):2419925. (#co-corresponding author) (JCR IF: 5.4)

 

24. Park E, Park S, Lee SJ, Jeong D, Jin H, Moon H, Cha B, Kim D, Ma S, Seo W, Han SH, Lee YS, Kang S. Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis. J Med Chem. 2023 14;66(23):16342-16363. (JCR IF: 8.039) 

 

23. Ho YC, Geng X, O'Donnell A, Ibarrola J, Fernandez-Celis A, Varshney R, Subramani K, Azartash-Namin ZJ, Kim J, Silasi R, Wylie-Sears J, Alvandi Z, Chen L, Cha B, Chen H, Xia L, Zhou B, Lupu F, Burkhart HM, Aikawa E, Olson LE, Ahamed J, López-Andrés N, Bischoff J, Yutzey KE, Srinivasan RS. PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circ Res. 2023 133(6):463-480. (JCR IF:20.1)

- Highlighted as Cover article

 

22. Park S, Das R, Nhiem NX, Jeong SB, Kim M, Kim D, Oh HI, Cho SH, Kwon OB, Choi JH, Park CS, Kim SR, Moon UY, Cha B, Choi DK, Lee S, Namkung W, Woo J, Seo Y. ANO1-downregulation induced by schisandrathera D: a novel therapeutic target for the treatment of prostate and oral cancers. Front Pharmacol. 2023 18;14:1163970. (JCR IF:5.6)

 

21. Cho HG, Moon SK, Jeong IH, Lee YE, Lee HK, Han BS, Kim Y, Chung YS, Cha B#, Kim W#. Virus detection of measles-negative cases in Gyeonggi Province, South Korea, from 2017 to 2019. Microbiol Immunol. 2022 67(3):160-165. (#co-corresponding author) (JCR IF: 2.962)

 

20. Cha B#, Moon S, Kim W#. A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development. BMB Rep. 2021 54(6):285-294 (#co-corresponding author) (JCR IF: 5.04)

 

19. Cha B*,#, Ho YC*, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS#. YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 13;147(23):dev195453. (*co-first author, #co-corresponding author) (JCR IF: 6.868)

- Highlighted as Cover article

 

18. Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe J, Mikelis CM, Hla T, Srinivasan RS. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 16:137652. (JCR IF: 9.48)

 

17. Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS. GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 5;146(21). (JCR IF: 5.763)

 

16. Yang Y, Cha B, Motawe ZY, Srinivasan RS, Scallan JP. VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance. Cell Rep. 2019 Aug 27;28(9):2397-412. (JCR IF: 7.815)

 

15. Kim W, Cho YS, Wang X, Park O, Ma X, Kim H, Gan W, Jho EH, Cha B, Jeung YJ, Zhang L, Gao B, Wei W, Jiang J, Chung KS, Yang Y. Hippo signaling is intrinsically regulated during cell cycle progression by APC/CCdh1. Proc Natl Acad Sci U S A. 2019 7;116(19):9423-9432. (JCR IF: 9.58)

 

14. Choi D, Park E, Jung E, Cha B, Lee S, Yu J, Kim PM, Lee S, Hong YJ, Koh CJ, Cho CW, Wu Y, Li Jeon N, Wong AK, Shin L, Kumar SR, Bermejo-Moreno I, Srinivasan RS, Cho IT, Hong YK. Piezo1 incorporates mechanical force signals into the genetic program that governs lymphatic valve development and maintenance. JCI Insight. 2019 7;4(5). pii: 125068. (JCR IF: 7.815) 

 

13. Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MI, Srinivasan RS. Complementary Wnt sources regulate lymphatic vascular development via PROX1-dependent Wnt/β-catenin signaling. Cell Reports. 2018 16;25(3):571-584.e5. (JCR IF: 7.815)

- Highlighted as Cover article

 

12. Kim W, Khan SK, Liu Y, Xu R, Park O, He Y, Cha B, Gao B, Yang Y. Hepatic Hippo signaling inhibits protumoural microenvironment to suppress hepatocellular carcinoma. Gut. 2018 67(9):1692-1703. (JCR IF: 17.01)

 

11. Geng X, Cha B, Mahamud MR, Srinivasan RS. Intraluminal valves: development, function and disease. Dis Model Mech. 2017 1;10(11):1273-1287. (JCR IF: 4.691)

 

10. Cho SJ*, Cha BS*, Kwon OS, Lim J, Shin DM, Han DW, Ishitani T, Jho EH, Fornace AJ, Cha HJ. Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development. Biochim Biophys Acta Mol Basis Dis. 2017 1863(4):1013-1022. (*co-first author) (JCR IF: 5.464)

 

9. Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, Kim J, Lee T, Cha B, Kim M, Kim H, Katanaev VL, Jho EH. Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization. EMBO Rep. 2017 18(1):61-71. (JCR IF: 8.568)

- Highlighted in News & Views in EMBO Rep 2017 Jan; 18(1): 3-4

 

8. Cha B, Srinivasan RS. Mechanosensitive β-catenin signaling regulates lymphatic vascular development. BMB Rep. 2016 49(8):403-4. (JCR IF: 5.04)

 

7. Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS. Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 15;30(12):1454-69. (JCR IF: 10.042)

- Highlighted as Cover article

 

6. Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS. Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 409(1):218-33. (JCR IF: 3.15)

- Highlighted as Cover article

 

5. Cha B*, Park Y*, Hwang BN, Kim SY, Jho EH. Protein Arginine Methyltransferase 1 Methylates Smurf2. Mol Cells. 2015 38(8):723-8. (*co-first author) (JCR IF: 2.09)

 

4. Kim W, Kim H, Katanaev VL, Lee SJ, Ishitani T, Cha B, Han JK, Jho EH.  Dual functions of DP1 promote and stabilize biphasic Wnt-on and Wnt-off states during anteriorposterior neural patterning. EMBO J. 2012 15;31(16):3384-97. (JCR IF: 9.025)

 

3. Cha B, Jho EH. Protein arginine methyltransferases (PRMTs) as therapeutic targets.

Expert Opin Ther Targets. 2012 16(7):651-64. (JCR IF: 4.13)

 

2. Cha B*, Kim W*, Kim YK, Hwang BN, Park SY, Yoon JW, Park WS, Cho JW, Bedford MT, Jho EH. Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling. Oncogene. 2011 19;30(20):2379-89. (*co-first author) (JCR IF: 7.414)

 

1. Kim H, Won S, Hwang DY, Lee JS, Kim MS, Kim R, Kim W, Cha B, Kim T, Kim D, Costantini F and Jho EH. Down-regulation of Wnt/β-catenin signaling causes degeneration of hippocampal neurons in vivo. Neurobiol Aging. 2011 32(12):2316.e1-15. (JCR IF: 6.634)