2006.02 중앙대학교 생명과학과 이학사 졸업

2007.08 중앙대학교 생명과학과 이학석사 졸업

2010.08 중앙대학교 생명과학과 이학박사 졸업 

2010 - 2013 중앙대학교 생명과학과 미생물학연구실 Post-Doc.

2013 - 2018 중앙대학교 약학대학 예방약학연구실 Post-Doc.

2018 - 2023 중앙대학교 생명과학과 연구교수

2024 - 현재 대구가톨릭대학교 의과대학 의예과 조교수

1. Yeom J-H*, Shin E*, Jin H*, Liu H, Luo Y, Nam Y, Ryu M, Song W, Chi H, Kim J, Lee K and Bae J. Aptamer-conjugated gold nanoparticles platform as the intracellular delivery of antibodies for cancer therapy. J Ind Eng Chem. (2023) Oct 25; 126: 480-491. *co-first author

2. Choi Y*, Shin E*, Lee M, Yeom J-H, and Lee K. Functional conservation of specialized ribosomes bearing genome-encoded variant rRNAs in Vibrio species. PLoS ONE (2023) Dec 5; 18(12): e0289072. *co-first author

3. Bae D, Hyeon H, Shin E, Yeom J-H, and Lee K. Relaxed Cleavage Specificity of Hyperactive Variants of Escherichia coli RNase E on RNA I. J Microbiol. (2023) Feb 1; 61(2): 2211-220. doi: 10.1007/s12275-023-00013-z.

4. Choi Y*, Joo M*, Song W*, Lee M, Jun H, Hyeon H, Kim H-L, Yeom J-H, Lee K†, and Shin E^†. Transcript-specific selective translation by specialized ribosomes bearing genome-encoded heterogeneous rRNAs in V. vulnificus CMCP6. J Microbiol. (2022) Dec 1; 60(12): 1162-1167. doi: 10.1007/s12275-022-2437-9. †co-corresponding

5. Joo M*, Yeom J-H*, Choi Y, Jun H, Song W, Kim H-L, Lee K†, and Shin E†. Specialised ribosomes as versatile regulators of gene expression. RNA Biology. (2022) Oct 18; 19(1):1103-1114. doi:10.1080/15476286.2022.2135299. †co-corresponding (Review)

6. Lee J*, Shin E*, Yeom J-H, Park J, Kim SW, Lee M, and Lee K. Regulator of RNase E activity modulates the pathogenicity of Salmonella Typhimurium. Microb Pathog. (2022) Feb 26;165:105460. doi:10.1016/j.micpath.2022.105460. *co-first author

7. Park J*, Shin E*, Yeom J-H, Choi Y, Joo M, Lee M, Kim JH, Bae J, and Lee K. Gold nanoparticle-DNA aptamer-assisted delivery of antimicrobial peptide effectively inhibits Acinetobacter baumannii infection in mice. J Microbiol. (2022) Jan; 60(1): 128-136 *co-first author

8. Lee J*, Shin E*, Park J, Lee M, and Lee K. Regulator of ribonuclease activity modulates the pathogenicity of Vibrio vulnificus. J Microbiol. (2021) Dec;59(12):1133-1141 *co-first author

9. Lee M, Ryu M, Joo M, Seo Y-J, Lee J, Kim H-M, Shin E, Yeom J-H, Kim Y-H, Bae J, and Lee K. Endoribonuclease-mediated control of hns mRNA stability constitutes a key regulatory pathway for Salmonella Typhimurium pathogenicity island 1 expression. PLoS Pathog. (2021) Feb 1; 17(2): e1009263. doi.org/10.1371/journal ppat.1009263

10. Moore C. J*, Go H*, Shin E*, Ha H-J, Song S, Ha N-C, Kim Y-H, Cohen S. N. Lee K. Substrate-dependent effects of quaternary structure on RNase E activity. Genes Dev. (2021) Jan 14; 35:286–299 doi: 10.1101/gad.335828.119 *co-first author

11. Shin E*, Jin H*, Suh DS*, Luo Y, Ha HJ, Kim TH, Hahn Y, Hyun S, Lee K, Bae J. An alternative miRISC targets a cancer‐associated coding sequence mutation in FOXL2. EMBO J. (2020) Dec 15; 39(24): e104719. *co-first author

12. Song W*, Joo M*, Yeom JH*, Shin E*, Lee M*, Choi HK, Hwang J, Kim YI, Seo R, Lee JE, Moore CJ, Kim YH, Eyun SI, Hahn Y, Bae J, Lee K. Divergent rRNAs as regulators of gene expression at the ribosome level. Nat Microbiol. (2019) Mar;4(3):515-526. *co-first author

13. Won M, Luo Y, Lee DH, Shin E, Suh DS, Kim TH, Jin H, Bae J. BAX is an essential key mediator of AP5M1-induced apoptosis in cervical carcinoma cells. Biochem Biophys Res Commun. (2019) Oct 15;518(2):368-373

14. Jin H, Won M, Shin E, Kim HM, Lee K, Bae J. EGR2 is a gonadotropin-induced survival factor that controls the expression of IER3 in ovarian granulosa cells. Biochem Biophys Res Commun. (2017) Jan 22;482(4):877-882.

15. Lim B, Sim M, Lee H, Hyun S, Lee Y, Hahn Y, Shin E †, Lee K†. Regulation of Escherichia coli RNase III activity. J Microbiol. (2015) Aug;53(8):487-94. †co-corresponding (Review)

16. Suh DS, Oh HK, Kim JH, Park S, Shin E, Lee K, Kim YH, Bae J. Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors. J Proteome Res. (2015) Jun 5;14(6):2446-56.

17. Kim D, Song S, Lee M, Go H, Shin E, Yeom JH, Ha NC, Lee K, Kim YH. Modulation of RNase E activity by alternative RNA binding sites. PLoS One. (2014) Mar 5;9(3):e90610.

18. Park M*, Shin E*, Won M, Kim JH, Go H, Kim HL, Ko JJ, Lee K, Bae J. FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells. Mol Endocrinol. (2010) May 24(5):1024-36. *co-first author

19. Sim SH, Yeom JH, Shin C, Song WS, Shin E, Kim HM, Cha CJ, Han SH, Ha NC, Kim SW, Hahn Y, Bae J, Lee K. Escherichia coli ribonuclease III activity is downregulated by osmotic stress: consequences for the degradation of bdm mRNA in biofilm formation. Mol Microbiol. (2010) Jan 75(2):413-25.

20. Yeom JH, Go H, Shin E, Kim HL, Han SH, Moore CJ, Bae J, Lee K. Inhibitory effects of RraA and RraB on RNAse E-related enzymes imply conserved functions in the regulated enzymatic cleavage of RNA. FEMS Microbiol Lett. (2008) Aug 285(1), 10-15.

21. Shin E*, Go H*, Yeom JH, Won M, Bae J, Han SH, Han K, Lee Y, Ha NC, Moore CJ, Sohlberg B, Cohen SN, Lee K. Identification of amino acid residues in the catalytic domain of RNase E essential for survival of Escherichia coli: functional analysis of DNase I subdomain. Genetics (2008) Aug 179(4), 1871-1879. *co-first author

22. Kim HL, Shin E, Kim HM, Go H, Roh J, Bae J, Lee K. Heterogeneous rRNA molecules encoded by Streptomyces coelicolor M145 genome are all expressed and assembled into ribosomes. J Microbiol Biotechnol. (2007) Oct 17(10), 1708-1711.

23. Kim HL, Shin EK, Kim HM, Ryou SM, Kim S, Cha CJ, Bae J, Lee K. Heterogeneous rRNAs are differentially expressed during the morphological development of Streptomyces coelicolor. FEMS Microbiol Lett. (2007) Oct 275(1), 146-152