홍재우 교수 (Jaewoo Hong)

홍재우 교수 이미지

전문분야
종양생리학, 면역생리학
전화번호
053-650-4247
이메일
jhong@cu.ac.kr
  • 학력사항

    2006-2012      건국대학교 의생명과학과 (이학박사)

    2000-2006      건국대학교 수의학과 (수의학사)

  • 경력사항

    2024-현재.     주식회사 캐니캐티케어(CaniCatiCare) 창업자, 대표이사

    2022-현재      대구가톨릭대학교 반려동물보건학과 겸임교수

    2020-현재      대구가톨릭대학교 의과대학 조교수

    2020              미국 Teraimmune inc. 프로젝트매니저, 연구원

    2013-2020    미국 National Institutes of Health (NIH), Research Fellow

    2012-현재      Frontiers in Immunology 저널, Associate Editor

    2012-2013    Brigham and Women’s Hospital, Harvard Medical School, Postdoctoral Fellow

    2006              수의사 면허 취득

  • 학회활동

    2012-현재       The American Association of Immunologists (AAI), 정회원

    2018-현재       The American Society for Cell Biology (ASCB), International Affairs Committee 위원

    2018-현재       The American Association of for Cancer Research (AACR), 정회원

    2019-현재       The Korean Association of Immunologists (대한면역학회)

    2021-현재        대한 생리학회, 학술위원

    2022-현재        American Physiological Society, International Committee 위원

  • 주요논문

    1.         Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target. Immune Netw, 2021. 21(1): p. e8.

    2.         Vav1 is Essential for HIF-1alpha Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells. Cancers (Basel), 2020. 12(6).

    3.         The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1alpha and Glut-1 Expression and Glucose Uptake in the Brain. Int J Mol Sci, 2020. 21(4).

    4.         Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation. Cancers (Basel), 2019. 11(11).

    5.         Neutrophilic Granule Protein Is a Novel Murine LPS Antagonist. Immune Netw, 2019. 19(5): p. e34.

    6.         Interleukin-33 and ST2 Signaling in Tumor Microenvironment. J Interferon Cytokine Res, 2019. 39(1): p. 61-71.

    7.         Proinsulin Shares a Motif with Interleukin-1alpha (IL-1alpha) and Induces Inflammatory Cytokine via Interleukin-1 Receptor 1. J Biol Chem, 2016. 291(28): p. 14620-7.

    8.         Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8. Proc Natl Acad Sci U S A, 2015. 112(8): p. 2497-502.

    9.         Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33. Proc Natl Acad Sci U S A, 2015. 112(23): p. 7249-54.

    10.       Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc Natl Acad Sci U S A, 2014. 111(7): p. 2650-5.

    11.       The inhibitory function of Fc-ST2 depends on cell type; IL-1RAcP and ST2 are necessary but insufficient for IL-33 activity. Immunol Res, 2013. 56(1): p. 122-30.

    12.       Amino acid differences in interferon-tau (IFN-tau) of Bos taurus Coreanae and Holstein. Cytokine, 2012. 59(2): p. 273-9.

    13.       The contradictory functions (activation/termination) of neutrophil proteinase 3 (PR3) in IL-33 biological activity. J Biol Chem, 2012.

    14.       Identification of constitutively active interleukin 33 (IL-33) splice variant. J Biol Chem, 2011. 286(22): p. 20078-86.

    15.       Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta. Cytokine, 2010. 49(2): p. 171-6.

    16.       Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis. Proc Natl Acad Sci U S A, 2010. 107(49): p. 21082-6.