김용학 교수
1985–1989: 서울대학교 자연과학대학 미생물학과, 이학사
1989–1992: 서울대학교 자연과학대학 미생물학과, 이학석사
1994–1999: 독일 Universität Stuttgart, 미생물학, 이학박사 (Dr. rer. nat.)
1999 - 2002: US FDA-National Center for Toxicological Research, Post-Doc
2003 - 2004: Canada NRC-Biotechnology Research Institute, Post-Doc
2005 - 2006: 서울대학교 생명과학부 박사후 연구원
2006 - 2008: 서울대학교 생명과학부 연구교수
2008 - 2010: 프로테오믹스이용기술개발사업단 (KIST) 선임연구원
2010 - 현재: 대구가톨릭대학교 조교수
2000 - 미국미생물학회 (ASM) 평회원
2007 - 한국생화학분자생물학회 평회원
=2015=
1. Saemee Song, Boeun Lee, Ji-Hyun Yeom, Soonhye Hwang, Ilnam Kang, Jang-Cheon Cho, Nam-Chul Ha, Jeehyeon Bae, Kangseok Lee*, Yong-Hak Kim* (*co-corresponding authors) (Epub ahead 2015.08.12) An MdsABC-mediated pathway for pathogenicity in Salmonella Typhimurium. Infection and Immunity. in press.
2. Yong-Hak Kim, Wooseok Song, Jin-Sik Kim, Li Jiao, Kangseok Lee, Nam-Chul Ha. (2015.5.29) Structural and mechanistic insights into the Pseudomonas fluorescens 2-nitrobenzoate 2-nitroreductase NbaA. Applied and Environmental Microbiology, 81(15): 5266-5277.
3. Dae-Shik Suh, Hoon Kyu Oh, Jae-Hong Kim, Seeun Park, Kangseok Lee, Yong-Hak Kim*, Jeehyeon Bae* (*co-corresponding authors) (2015.04.15) Identification and validation of differential phosphorylation sites of the nuclear FOXL2 protein as potential, novel biomarkers for adult-type granulosa cell tumors. Journal of Proteome Research. 14(6): 2446-2456.
=2014=
1. Jin-Sik Kim, Li Jiao, Jeong-Il Oh, Nam-Chul Ha*, Yong-Hak Kim* (2014.07.17) Crystal structure and functional implications of LprF from Mycobacterium tuberculosis and bovis. Acta Crystallographica Section D: Biological crystallography 70: 2619-2630.
2. Bo-Young Yoon, Jin-Sik Kim, Si-Hyeon Um, Inseong Jo, Jin-Wook Yoo, Kangseok Lee, Yong-Hak Kim, Nam-Chul Ha (2014.04.18) Periplasmic disulfide isomerase DsbC is involved in the reduction of copper binding protein CueP from Salmonella enterica serovar Typhimurium. Biochemical and Biophysical Research Communications. 446(4):971-976.
3. Daeyoung Kim, Saemee Song, Minho Lee, Hayoung Go, Eunkyoung Shin, Ji-Hyun Yeom, Nam-Chul Ha, Kangseok Lee*, Yong-Hak Kim* (co-corresponding authors) (2014.03.05). Modulation of RNase E activity by alternative RNA binding sites. PLoS ONE 9: e90610.
4. Bo-Young Yoon, Ji-Hyun Yeom, Jin-Sik Kim, Si-Hyeon Um, Inseong Jo, Kangseok Lee, Yong-Hak Kim*, Nam-Chul Ha*(co-corresponding authors) (2014.02.28). Direct ROS scavenging activity of CueP from Salmonella enterica serovar Typhimurium. Molecules and Cells 37: 100-108.
5. Wooseok Song*, Yong-Hak Kim* (co-first authors), Se-Hoon Sim, Soonhye Hwang, Jung-Hyun Lee, Younghoon Lee, Jeehyeon Bae, Jihwan Hwang, Kangseok Lee. (2014.01.30) Antibiotic stress-induced modulation of the endoribonucleolytic activity of RNase III and RNase G confers resistance to aminoglycoside antibiotics in Escherichia coli. Nucleic Acids Research, doi:10.1093/nar/gku093.
6. Jae-Hong Kim*, Yong-Hak Kim* (co-first authors), Hong-Man Kim , Ho-Oak Park , Nam-Chul Ha , Tae Hoen Kim , Mira Park , Kangseok Lee, Jeehyeon Bae. (2014.01.03) FOXL2 posttranslational modifications by GSK3β-mediated serine 33 phosphorylation determine the growth of granulosa cell tumors. Nature Communications 5, doi:10.1038/ncomms3936.
=2013=
1. Bo-Young Yoon, Yong-Hak Kim, Nahee Kim, Bo-Young Yun, Jin-Sik Kim, Joon-Hee Lee, Hyun-Soo Cho, Kangseok Lee, Nam-Chul Ha (2013.09.15). Structure of the periplasmic copper-binding protein CueP from Salmonella enterica serovar Typhimurium. Acta Crystallographica Section D: Biological Crystallography 69: 1867-1875.
2. Yong-Hak Kim, Woo-Seok Song, Hayoung Go, Chang-Jun Cha, Cheolju Lee, Myeong- Hee Yu, Peter C.K. Lau, Kangseok Lee (2013.01.15) 2-Nitrobenzoate 2-nitroreductase (NbaA) switches its substrate specificity from 2-nitrobenzoic acid to 2,4-dinitrobenzoic acid under oxidizing conditions. Journal of Bacteriology 195(2): 180-192.
=2012=
1. Yong-Hak Kim, Myeong-Hee Yu. (2012.06.01) Overexpression of reactive cysteine-containing 2-nitrobenzoate nitroreductase (NbaA) and its mutants alters the sensitivity of Escherichia coli to reactive oxygen species by reprogramming a regulatory network of disulfide-bonded proteins. Journal of Proteome Research 11(6): 3219-3230.
=2011=
1. Hayoung Go, Christopher J. Moore, Minho Lee, Eunkyoung Shin, Che Ok Jeon, Chang-Jun Cha, Seung Hyun Han, Su-Jin Kim, Sang-Won Lee, Younghoon Lee, Nam-Chul Ha, Yong-Hak Kim* (*co-corresponding authors), Stanley N. Cohen*, Kangseok Lee*. (2011.11.01) Upregulation of RNase E activity by mutation of a site that uncompetitively interferes with RNA binding. RNA Biology 8(6): 1022-1034.
2. Kim, Y.-H., Kim, I.S., Moon, E.Y., Park, J.S., Kim, S.-J., Lim, J., Park, B.T., Lee, E.J. (2011.09.15). High abundance and role of antifungal bacteria in compost-treated soils in a wildfire area. Microbial Ecology 62: 725-737.
3. Mun, J., Kim, Y.-H., Yu, J., Bae, J., Noh, D.-Y., Yu, M.-H., Lee, C. (2011.03.29) A proteomic approach based on multiple parallel separation for the unambiguous identification of an antibody cognate antigen. Proteomics Clinical Applications 5(3-4): 207. Biomedical Abstract.
=2010=
1. Mun, J., Kim, Y.-H., Yu, J., Bae, J., Noh, D.-Y., Yu, M.-H., Lee, C. (2010.09.24) A proteomic approach based on multiple parallel separation for the unambiguous identification of an antibody cognate antigen. Electrophoresis 31: 3428-3436.
2. Kang, U.-B., Ahn, Y., Lee, J.W., Kim, Y.-H., Kim, J., Yu, M.-H., Noh, D.-Y., Lee, C. (2010.03.26) Differential profiling of breast cancer plasma proteome by isotope-coded affinity tagging method reveals biotinidase as a breast cancer biomarker. BMC Cancer 10:114.
3. Thorenoor, N., Lee, J.-H., Lee, S.-K., Cho, S.-W., Kim, Y.-H., Kim, K.-S., Lee, C. (2010.02.23) Localization of FADD-DED into the membrane of Escherichia coli induces ROS-involved cell death. Biochemistry 49(7): 1435-1447.
4. Kim, Y.-H., Lee, C., Go, H., Konishi, K., Lee, K., Lau, P.C.K., Yu, M.-H. (2010.02.15) Decolorization of malachite green by cytochrome c in the mitochondria of the fungus Cunninghamella elegans. Archives of Biochemistry and Biophysics 494: 159-165.
=2009=
1. Thorenoor, N., Kim, Y-H.*(corresponding author), Lee, C., Yu, M.-H., and Engesser, K.-H. (2009.06.01) A previously uncultured, paper mill Propionibacterium is able to degrade O-aryl alkyl ethers and various aromatic hydrocarbons. Chemosphere 75: 1287-1293.
2. Yoon, S., Ha, H.-J., Kim, Y.-H., Won, M., Park, M., Ko, J.-J., Lee, K., Bae, J. (2009.05.01) IEX-1-induced cell death requires BIM and is modulated by MCL-1. Biochemical and Biophysical Research Communications 382, 400-404.
3. Kim, D.-H., Bae, J., Lee, J.W., Kim, S.-Y., Bae, J.-Y., Yi, J.K., Kim, Y.-H., Yu, M.-H., Noh, D.-Y., Lee, C. (2009.01.01) Proteomic analysis of breast cancer tissue reveals up-regulation of actin-remodeling proteins and its relevance to cancer invasiveness. Proteomics Clinical Applications 3: 30-40.
=2008=
1. Kim, Y.-H., Cha, C.-J., Engesser, K.-H., Kim, S.-J. (2008.11.01) Degradation of various alkyl ethers by alkyl ether-degrading Actinobacteria isolated from activated sludge of a mixed wastewater treatment. Chemosphere 73: 1442-1447.
=2007=
1. Kim, Y.-H., Engesser, K.-H., Kim, S.-J. (2007.06.01) Physiological, numerical, and molecular characterization of alkyl ether-utilizing rhodococci. Environmental Microbiology 9 (6): 1497-1510.
=2006=
1. Kim, Y.-H., Kang, I., Bergeron, H., Lau, P.C.K., Engesser, K.-H., Kim, S.-J. (2006.11.01) Physiological, biochemical, and genetic characterization of an alicyclic amine-degrading Mycobacterium sp. strain THO100 isolated from a morpholine-containing culture of activated sewage sludge. Archives of Microbiology 186(5): 425-434.
2. Kim, Y.-H., Kang, U.-B., Konishi, K., Lee, C. (2006.09.01) Rhodococcus sp. strain TM1 plays a synergistic role in the degradation of piperidine by Mycobacterium sp. strain THO100. Archives of Microbiology 186(3): 183-193.
=2005=
1. Kim, Y.–H., Engesser, K.–H., Cerniglia, C.E. (2005.07.01) Numerical and genetic analysis of polycyclic aromatic hydrocarbon-degrading mycobacteria. Microbial Ecology 50(1):110-119.
2. Kim, Y.–H., Cerniglia, C.E. (2005.07.01) Influence of erythromycin A on the microbial populations in aquaculture sediment microcosms. Aquatic Toxicology 73(3):230-241.
3. Kim, Y.–H., Pothuluri, J.V., Cerniglia, C.E. (2005.07.01) Voltammetric investigation of macrolides by the HPLC-coulometric assay. Journal of Pharmaceutical and Biomedical Analysis 38(3):390-396.
4. Kim, Y.–H., Moody, J.D., Freeman, J.P., Engesser, K.–H., Cerniglia, C.E. (2005.04.01) Effects of pH on the degradation of phenanthrene and pyrene by Mycobacterium vanbaalenii PYR-1. Applied Microbiology and Biotechnology 67(2): 275-285.
5. Kim, Y.–H., Engesser, K.–H. (2005.02.15) Inhibition of diethyl ether degradation in Rhodococcus sp. strain DEE5151 by glutaraldehyde and ethyl vinyl ether. FEMS Microbiology Letters 243(2):317-322.
=2004=
1. Kim, Y.–H., Moody, J.D., Freeman, J.P., Brezna, B., Engesser, K.–H., Cerniglia, C.E. (2004.12.01) Evidence for the existence of PAH-quinone reductases and catechol-O-methyltransferase in Mycobacterium vanbaalenii PYR-1. Journal of Industrial Microbiology & Biotechnology 31(11): 507-516.
2. Kim, Y.–H., Engesser, K.–H. (2004.07.01) Degradation of alkyl ethers, aralkyl ethers, and dibenzyl ether by Rhodococcus sp. strain DEE5151, isolated from diethyl ether-containing enrichment cultures. Applied and Environmental Microbiology 70(7): 4398-4401.
3. Kim, Y.–H., Pak, K., Pothuluri, J.V., Cerniglia, C.E. (2004.05.01) Mineralization of erythromycin A in aquaculture sediments. FEMS Microbiology Letters 234(1): 169-175.
4. Kim, Y.–H., Heinze, T.M., Beger, R., Pothuluri, J.V., Cerniglia, C.E. (2004.03.01) A kinetic study on the degradation of erythromycin A in aqueous solution. International Journal of Pharmaceutics 271(1): 63-76.
5. Kim, Y.–H., Heinze, T.M., Kim, S.J., Cerniglia, C.E. (2004.01-02) Adsorption and clay-catalyzed degradation of erythromycin A on homoionic clays. Journal of Environmental Quality 33(1): 257-264.
=2003=
1. Kim, Y.-H., Kim, C.S., Park, S., Han, S.Y., Pyo, M.-Y., Yang, M. (2003.12.12) Gender differences in the levels of bisphenol A metabolites in urine. Biochemical and Biophysical Research Communications 312(2): 441-448.
2. Kim, Y.–H., Engesser, K.–H., Cerniglia, C.E. (2003.08.15) Two polycyclic aromatic hydrocarbon o-quinone reductases from a pyrene-degrading Mycobacterium. Archives of Biochemistry and Biophysics 416(2): 209-217.
=2002=
1. Cha, C.J., Kim, S.J., Kim, Y.–H., Stingley, R., Cerniglia, C.E. (2002.12.12) Molecular cloning and expression of genes encoding a novel class of glutathione S-transferases from the fungus Cunninghamella elegans. Biochemical Journal 368(2): 589-595.
2. Kim, Y.-H., Cha, C.J., Cerniglia, C.E. (2002.05.07) Purification and characterization of an erythromycin esterase from an erythromycin-resistant Pseudomonas sp. FEMS Microbiology Letters 210(2): 239-244.
=2001=
1. Min, K.-L., Kim, Y.–H., Kim, Y.W., Jung, H.S., Hah, Y.C. (2001.08.15) Characterization of a novel laccase produced by the wood-rotting fungus Phellinus ribis. Archives of Biochemistry and Biophysics 392(2): 279-286.